Equipe Tubuline et protéines associées

Email : claire [dot] heichette [at] univ-rennes1 [dot] fr

Phone : +33 (0)2 23 23 68 41


Université de Rennes 1
UMR 6290, équipe TIPs
Campus de Beaulieu, Bât. 13, Pièce 215
35042 Rennes Cedex

In a few words

Claire Heichette obtained her diploma of Technician in Biochemistry in 1997 (Lycée Talensac, Nantes). In 1999, she joined the UMR 6026 "Cell and Molecular Interactions" of Rennes, in the teams "Structure and Dynamics of the Cytoskeleton" (Denis Chrétien), and "Channels and Membrane Receptors" (Daniel Thomas). She then belonged to the teams "Structure and Dynamics of Macromolecules" (2004-2007) and "Tubulin and Interacting Proteins" (since 2007) leaded by Denis Chrétien. In 2007, she obtained the grade of Technician in Biology, speciality Electron Microscopy, and in 2010 the grade of Technician in Biology, Class Exceptional. Claire shares today her activities between the functioning of the laboratory (lab manager) and that of the IGDR (prevention agent). She also teaches in the cryo-electron tomography workshops organized every year by the team.


Lab manager

Health and Security Officer

Member of the Laboratory Council

Selected publications

Trehalose prevents aggregation of exosomes and cryodamage
Bosch S., de Beaurepaire L., Allard M., Mosser M., Heichette C., Chrétien D., Jegou D., and J.-M. Bach
Scientific Reports, 2016 Nov.

EB1 interacts with outwardly curved and straight regions of the microtubule lattice
Guesdon A*, Bazile F*, Buey RM, Mohan R, Monier S, Rodríguez García R, Angevin M, Heichette C, Wieneke R, Tampé R, Duchesne L, Akhmanova A, Steinmetz MO, Chrétien D
Nat Cell Biol. 2016, Sep.
*Co-first authors

Cryo-electron tomography of microtubules assembled in vitro from purified components
Coquelle F., Blestel S., Heichette C., Arnal I., Kervrann C., Chrétien D
Methods Mol Biol, 2011 Jun.

The 90-kDa heat shock protein HSP90 protects tubulin against thermal denaturation
Weis, F., Moullintraffort, L., Heichette, C., Chrétien, D., Garnier, C
J Biol Chem, 2010, Mar.

Second harmonic microscopy of axonemes
Odin, C., Heichette, C., Chrétien,D., and Y. Le Grand
Opt Express, 2009 May.

EB1 regulates microtubule dynamics and tubulin sheet closure in vitro
Vitre B, Coquelle FM, Heichette C, Garnier C, Chrétien D, Arnal I
Nat Cell Biol, 2008 Apr.

CLIP-170/tubulin-curved oligomers coassemble at microtubule ends and promote rescues
Arnal I, Heichette C, Diamantopoulos GS, Chrétien D
Curr Biol, 2004 Dec.