Gene Expression and Development Group Publications

Publications 2014-2020

>2020

The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development.
Sandeep Aryal#, Justine Viet#, Bayley AT Weatherbee#, Archana D Siddam, Francisco G Hernandez, Carole Gautier-Courteille, Luc Paillard&, Salil A Lachke &
Human Genetics 2020 Dec.

The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation
Franck Chesnel, Anne Couturier, Adrien Alusse, Jean-Philippe Gagné, Guy G Poirier, Dominique Jean, François-Michel Boisvert, Pauline Hascoet, Luc Paillard, Yannick Arlot-Bonnemains, Xavier Le Goff
PLoS Genet 2020 Nov.

Modeling ocular lens disease in Xenopus.
Justine Viet, David Reboutier, Serge Hardy, Salil A Lachke, Luc Paillard, Carole Gautier-Courteille
Dev Dyn. 2020 May

Synergistic defects in pre-rRNA processing from mutations in the U3-specific protein Rrp9 and U3 snoRNA.
Guillaume Clerget, Valérie Bourguignon-Igel, Nathalie Marmier-Gourrier, Nicolas Rolland, Ludivine Wacheul, Xavier Manival, Christophe Charron, Joanna Kufel, Agnès Méreau, Véronique Senty-Ségault, David Tollervey, Denis LJ Lafontaine, Christine Branlant, Matthieu Rederstorff.
Nucleic Acids Res. 2020 Apr.

Translational derepression of Elavl4 isoforms at their alternative 5’ UTRs determines neuronal development.
Tatiana Popovitchenko, Yongkyu Park, Nicholas F Page, Xiaobing Luo, Zeljka Krsnik, Yuan Liu, Iva Salamon, Jessica D Stephenson, Matthew L Kraushar, Nicole L Volk, Sejal M Patel, H R Sagara Wijeratne, Diana Li, Kandarp S Suthar, Aaron Wach, Miao Sun, Sebastian J Arnold, Wado Akamatsu, Hideyuki Okano, Luc Paillard, Huaye Zhang, Steven Buyske, Ivica Kostovic, Silvia De Rubeis, Ronald P Hart, Mladen-Roko Rasin
Nature Commun. 2020 Apr.

Reassembling green fluorescent protein for in vitro evaluation of trans-translation.
Charlotte Guyomar, Marion Thépaut, Sylvie Nonin-Lecomte, Agnès Méreau, Renan Goude, Reynald Gillet
Nucleic Acids Res. 2020 Jan.

>2019

CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation.
Chang Jiang, Stephen J Trudeau, Taek-Chin Cheong, Rui Guo, Mingxiang Teng, Liang Wei Wang, Zhonghao Wang, Chiara Pighi, Carole Gautier-Courteille, Yijie Ma, Sizun Jiang, Chong Wang, Bo Zhao, Luc Paillard, John G Doench, Roberto Chiarle, Benjamin E Gewurz
Cell Rep. 2019 Jul.

Xenopus Resources: Transgenic, Inbred and Mutant Animals, Training Opportunities, and Web-Based Support
Marko Horb, Marcin Wlizla, Anita Abu-Daya, Sean McNamara, Dominika Gajdasik, Takeshi Igawa, Atsushi Suzuki, Hajime Ogino, Anna Noble, Centre de Ressource Biologique Xenope team in France (Nicolas M, Lafond T, Boujard D, Audic Y, Guillet B), Jacques Robert, Christina James-Zorn, Matthew Guille
Front Physiol. 2019 Apr.

> 2018

Bruno-3 regulates sarcomere component expression and contributes to muscle phenotypes of myotonic dystrophy type 1.
Lucie Picchio, Vincent Legagneux, Stéphane Deschamps, Yoan Renaud, Sabine Chauveau, Luc Paillard, Krzystof Jagla
Dis Model Mech. 2018 May

The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development
Archana D. Siddam#, Carole Gautier-Courteille#, Linette Perez-Campos, Deepti Anand, Atul Kakrana, Christine A. Dang, Vincent Legagneux, Agnès Méreau, Justine Viet, Jeffrey M. Gross, Luc Paillard&, Salil A. Lachke&
PLoS Genet 2018 Mar.

RNA-Seq Analysis of an Antisense Sequence Optimized for Exon Skipping in Duchenne Patients Reveals No Off-Target Effect.
Claire Domenger, Marine Allais, Virginie François, Adrien Léger, Emilie Lecomte, Marie Montus, Laurent Servais, Thomas Voit, Philippe Moullier, Yann Audic, Caroline Le Guiner
Mol Ther Nucleic Acids 2018 Mar.

> 2017

When eukaryotes and prokaryotes look alike: the case of regulatory RNAs.
Brice Felden, Luc Paillard
FEMS Microbiol Rev. 2017 Sep.

Robust identification of Ptbp1-dependent splicing events by a junction-centric approach in Xenopus laevis
Maud Noiret, Agnès Méreau, Gaëlle Angrand, Marion Bervas, Carole Gautier-Courteille, Vincent Legagneux, Stéphane Deschamps, Hubert Lerivray, Justine Viet, Serge Hardy, Luc Paillard, Yann Audic
Dev Biol 2017 Jun.
Link to R scripts and data

United we stand: big roles for small RNA gene clusters
Brice Felden, Luc Paillard
RNA 2017 Feb.

> 2016

Identification of CELF1 RNA targets by CLIP-seq in human HeLa cells.
Le Tonquèze O, Gschloessl B, Legagneux V, Paillard L, Audic Y.
Genom Data. 2016 Apr.

Ptbp1 and Exosc9 knockdowns trigger skin stability defects through different pathways.
Noiret M, Mottier S, Angrand G, Gautier-Courteille C, Lerivray H, Viet J, Paillard L, Mereau A, Hardy S, Audic Y.
Dev Biol. 2016 Jan.

>2015

Hypogonadism Associated with Cyp19a1 (Aromatase) Posttranscriptional Upregulation in Celf1 Knockout Mice.
Boulanger G, Cibois M, Viet J, Fostier A, Deschamps S, Pastezeur S, Massart C, Gschloessl B, Gautier-Courteille C, Paillard L.
Mol Cell Biol. 2015 Sep.

A post-transcriptional mechanism that controls Ptbp1 abundance in Xenopus epidermis. 
Méreau A, Anquetil V, Lerivray H, Viet J, Schirmer C, Audic Y, Legagneux V, Hardy S, Paillard L.
Mol Cell Biol. 2015 Feb.

> 2014

Dynamic estrogen receptor interactomes control estrogen-responsive trefoil Factor (TFF) locus cell-specific activities.
Quintin J, Le Péron C, Palierne G, Bizot M, Cunha S, Sérandour AA, Avner S, Henry C, Percevault F, Belaud-Rotureau MA, Huet S, Watrin E, Eeckhoute J, Legagneux V, Salbert G, Métivier R. 
Mol Cell Biol. 2014 Jul.

Evaluating the effects of CELF1 deficiency in a mouse model of RNA toxicity.
Kim YK, Mandal M, Yadava RS, Paillard L, Mahadevan MS.
Hum Mol Genet. 2014 Jan

zfp36 expression delineates both myeloid cells and cells localized to the fusing neural folds in Xenopus tropicalis.
Noiret M, Hardy S, Audic Y.
Int J Dev Biol. 2014.

 

Book chapters

Study of RNA-protein interactions and RNA structure in ribonucleoprotein particles (RNP).
Marchand V, Mougin A, Mereau A, Behm-Ansmant I, Motori y , Branlant C.
In : Hartmann RK, Bindereif A, Schön A, Westhof E, Eds., 2014, Hand(44) Handbook on RNA biochemistry: second, completely revised and enlarged edition