IGDR DAY 2017

8:30

Schedule

8h30 : coffee/croissant welcoming

8h50 : introduction

NEWCOMERS PRESENTATION

9h-10h : Aurélien BIDAUD-MEYNARD - Audrey BROSSARD - Céline BURCKLE - Thibault COURTHEOUX - Awa DIOP - Thomas ESMANGART DE BOURMENVILLE – Anne FORESTIER - Rafael GOMES VON BOROWSKI - Renan GOUDE - Vincent GUEN - Siou KU - Jérôme LE DOUCE - Héloïse LECLAIR - Audrey LEJART - Anaïs PROUTEAU - Clara SAVARY - Marion THEPAUT

« FLASH » POSTERS PRESENTATIONS

10h-10h30 : Céline LE BEGUEC – Xavier LE GOFF – Siou KU & Awa DIOP - Vasantha RADHAKRISHNAN & Céline CALLENS - Houda HAMDI-ROZE - Jérémie GAUDICHON 

10h30-10h45 : coffee/posters break

10h45-12h00 :  Alexandre THOMAS - Sophie CHAT - Anne BOURDAIS - Dominique MIAS LUCQUIN - Thomas ESMANGART - Annabelle MONNIER - Carole GAUTIER-COURTEILLE - Yann LE CUNFF - Marie LE BOULCH - Audrey LAURENT -  Gilles LEMARCHAND & Florian SIZAIRE - Jenny WU - Adrien ALUSSE

THE GENERAL PUBLIC CONFERENCES

12h00-12h30 : Morgane OLLIVIER
" Paléogénomique : un outil magique ? "

12h45-13h45 : Lunch break around posters

13h45-14h30 : Guilia BERTOLIN 
" La mitochondrie : l'EDF de la cellule au service de notre santé "

Outstanding PUBLICATIONS

14h30- 14h55 : Denis CHRETIEN
« EB1 interacts with outwardly curved and straight regions of the microtubule lattice »
Guesdon A*, Bazile F*, Buey RM, Mohan R, Monier S, Rodríguez García R, Angevin M, Heichette C, Wieneke R, Tampé R, Duchesne L, Akhmanova A, Steinmetz MO, Chrétien D.
Nat Cell Biol. 2016 Sep.

14h55 – 15h20 : Ronan ULVÉ
« Discovery of human-similar gene fusions in canine cancers. »
Ulvé R, Rault M, Bahin M, Lagoutte L, Abadie J, De Brito C, Coindre JM, Botherel N, Rousseau A, Wucher V, Cadieu E, Thieblemont C, Hitte C, Cornevin L, Cabillic F, Bachelot L, Gilot D, Hennuy B, Guillaudeux T, Le Goff A, Derrien T, Hédan B, André C.
Cancer Res. 2017 Sep 7. pii: canres.2691.2016. doi: 10.1158/0008-5472.CAN-16-2691.

15h20 – 15h45 : Marc TRAMIER
« Multiplexing molecular tension sensors reveals piconewton force gradient across talin-1 »
Ringer P, Weißl A, Cost AL, Freikamp A, Sabass B, Mehlich A, Tramier M, Rief M, Grashoff C.
Nat Methods. (2017) 14:1090-1096.

15h45-16h15 : coffee/posters break

16h15- 16h40 : David GILOT
"A noncoding function of TYRP1mRNA promotes melanoma growth"
David Gilot, Mélodie Migault, Laura Bachelot, Fabrice Journé, Aljosja Rogiers, Emmanuelle Donnou-Fournet, Ariane Mogha, Nicolas Mouchet, Marie-Laure Pinel-Marie, Bernard Mari, Tristan Montier, Sébastien Corre, Arthur Gautron, Florian Rambow, Petra El Hajj, Rania Ben Jouira, Sophie Tartare-Deckert, Jean-Christophe Marine, Brice Felden, Ghanem Ghanem, & Marie-Dominique Galibert
Nat Cell Biol, 2017 Oct 9;19(11):1348-1357

16h40 – 17h05 : Gilles SALBERT
« Cytosine modifications modulate the chromatin architecture of transcriptional enhancers. »
Mahé EA, Madigou T, Sérandour AA, Bizot M, Avner S, Chalmel F, Palierne G, Métivier R, Salbert G.
Genome Res. 2017 Jun;27(6):947-958

17h05 : conclusion

POSTERS

Catherine ANDRÉ Group

Céline LE BEGUEC (flash) " Integrated genomic and transcriptomic analyses of canine long non-coding RNAs "

Solenne CORREARD « A dog spontaneous model for human sensory neuropathies: identification of a mutation in a regulatory region of the glial cell derived neurotrophic factor gene (GDNF) »

Yannick ARLOT Group

Xavier LE GOFF (flash) « Characterization of proteostasis network of human pVHL isoforms »

Adrien ALUSSE (flash) « In vitro 3D model in cancer research »

Chesnel F- Le Goff X - Le Goff C- Couturier A Alusse A - Jullion E  - Arlot Y « Proteomic and transcriptomic signature of pVHL isoform expression  to reveal the pVHL functions in cancer progression »

Denis CHRETIEN Group

Siou KU et Awa DIOP (flash) "Microtubule structure and dynamics"

Damien COUDREUSE Group

Vasanthakrishnan RADHAKRISHNAN BALASUBRAMANIAM & Céline CALLENS (flash) "Evolution of the cell cycle network: Impact of complexity on the lifespan of an organism"

Javier MUNOZ GARCIA “ Shaping the cell cycle: artificial oscillations in CDK activity”

Véronique DAVID Group

Houda HAMDI-ROZE (flash) "La régulation de SHH par la voie Notch, ou comment expliquer l’hétérogénéité phénotypique de l’holoprosencéphalie."

Artem KIM "The implication of multiple rare variants in complex genetic disorders: the case of holoprosencephaly"

Marie-Dominique GALIBERT Group

Jérémie GAUDICHON (flash) "Hypoxia Regulates the Expression of the Tetraspanin CD9 Through the HIF Pathway in Acute Lymphoblastic Leukemia".

Nina TARDIF "Chronic activation of Ah receptor (AhR) promotes BRAF inhibitor resistance in melanoma"

Regis GIET Group

Alexandre THOMAS (flash) "Mitotic spindle length and asymmetric cell division"

Reynald GILLET Group

Sophie CHAT (flash) "Analyse de particules isolées hydratées-congelées en cryo-microscopie électronique".

Rafael GOMES VON BOROWSKI "Bioactive peptides and peptidomimetics from Capsicum bacattum var. pendulum (SOLANACEAE) for anti-virulence action"

Guillaume HALET Group

Anne BOURDAIS (flash) "Investigating the role of PI3-kinase signalling in oocyte growth and meiosis via the targeted invalidation of the PIK3CA (p110alpha) gene in oocytes."

Jean-François HUBERT Group

Dominique MIAS LUCQUIN (flash) « How the myopathy related portein dystrophin can interact with both muscle cytoskeletal F-actin and sarcolemma phospholipids? »

Raphael DOS SANTOS MORAIS « Analysis of the 3D structure of dystrophin fragments in the presence of isotropic bicelles »

Roland LE BORGNE Group

Thomas ESMANGART DE BOURNONVILLE (flash) " Roles and assembly of tricellular junctions during epithelia cells division "

Elise HOUSSIN « Implication des  forces mécaniques et du remodelage de la polarité épithéliale dans la régulation de la signalisation Notch lors de la division cellulaire asymétrique »

Grégoire MICHAUX Group

Ophélie NICOLLE “Ultrastructure tools for intestinal tissue analysis: from C. elegans to rare congenital absorption disorders”

Aurélien BIDAUD-MEYNARD “Intestinal polarity is maintained by V0-ATPase-dependent apical sorting in C. elegans

Jean MOSSER Group

Annabelle MONNIER (flash) «  EMX2 induit un blocage réversible du cycle cellulaire dans des lignées de GBM »

Luc PAILLARD Group

Carole GAUTIER-COURTEILLE (flash) "Modeling eye diseases in Xenopus"

Yann AUDIC "Control of TP63 splicing in epithelia"

Jacques PECREAUX Group

Yann LE CUNFF (flash) : « Model-free analysis of spindle elongation trajectories in C. elegans one-cell embryo»

Laurent CHESNEAU “Dynamics of dyne at microtubule plus-end and the cortex during the division of the C. elegans zygote”

Claude PRIGENT Group

Arun Prasath DAMODARAN « Role of Aurora-A in pre-mRNA splicing »

Gwenaël RABUT Group

Marie LE BOULCH (flash) "Deciphering the network of ubiquitylation enzymes that regulate the centromeric Histone CENPA in budding yeast"

Gilles SALBERT Group

Audrey LAURENT (flash) « Modulation of 5mC oxidation: a strategy for MCF7 breast cancer cells reprogramming?"

Sébastien HUET « Detrended Fluorescence Correlation Spectroscopy : a tool to analyze the dynamic binding of repair proteins to DNA breaks. «

Marc TRAMIER Group

Gilles LE MARCHAND & Florian SIZAIRE (flash) "Automated inhibitor screening of Aurora A kinase activity based on a FRET biosensor"

Jenny WU Group

Jenny WU (flash d’introduction au poster de Blanca GOMEZ) « Copier et protéger l'ADN dans nos cellules »

Blanca GOMEZ "The organization of replication initiation regulates the profile of genomic instability"