2-year post-doctoral position available at the IGDR (Rennes, France)

2-year post-doctoral position available at the IGDR (Rennes, France)

Deciphering the impact of mitochondria on cell cycle progression

Job description

One post-doctoral position is available at the Institute of Genetics and Development of Rennes (https://igdr.univ-rennes1.fr/en), in the team of Dr. Marc Tramier and directly supervised by Dr. Giulia Bertolin. The position is available for a period of 2 years starting early 2020.

Research in our team focuses on state-of-the-art methods and techniques in quantitative fluorescence microscopy to investigate the spatiotemporal regulation of protein-protein interactions and biochemical activities in live cells (e.g. see Bertolin et al, eLife 2018, doi: 10.7554/eLife.38111 or Bertolin et al, ACS Sensors, 2019 10.1021/acssensors.9b00486).

Molecular programs for cell division and fate allow the cell to adapt to its changing needs. This requires high levels of energy, produced by mitochondria. However, how mitochondria control their functions during the cell cycle is heavily neglected. The team has a strong ongoing research axis relying on the combination of multiple FRET biosensors, biochemistry and live microscopy in human cells to follow mitochondrial physiology. The recruited post-doctoral fellow will be involved in the use of such experimental strategies in the context of cell cycle progression.

The IGDR is a dynamic and expanding institute, with 20 teams including more than 250 international researchers and staff. Research at the IGDR covers a wide range of subjects in cell biology, taking advantage of classical model systems while strongly promoting interdisciplinary approaches, particularly at the interface between physics and biology. The institute also benefits from state-of-the-art core facilities, particularly in microscopy (Microscopy Rennes Imaging Center, MRic, https://microscopie.univ-rennes1.fr/).

Rennes is the capital of Brittany, in northwestern France, with easy and direct access to Paris (around 1.5 hours by train). Its rich tradition of cultural, musical and artistic events, as well as its close proximity to the coast, makes it a very welcoming and pleasant place to live.

Qualifications

The applicant should hold a PhD in biology. Proven experience in cell biology applied to the study of mitochondrial functions and in fluorescence microscopy are a prerequisite. Some knowledge in the FRET field would be a plus. Candidates are expected to conduct research independently.

To be eligible, candidates must have spent at least 18 months outside of France between May 1st, 2016 and the beginning of the project. The Post-doc salary is calculated according to French national standards for post-docs. International applications are highly encouraged.

Contact

Applications should include a CV with a publication list, a cover letter and recommendation letters to be sent directly by at least two professional referees. The files should be sent to Dr. Giulia Bertolin (email: giulia.bertolin@univ-rennes1.fr).

 

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