CRB Cani-DNA

 

Cani-DNA: a French National biobank for canine samples for human and veterinary biomedical research.

Dog represents a spontaneous model of many genetic diseases including cancers and other multifactorial diseases as well as monogenic diseases. The last 15 years, genetic tools dedicated to dogs allowed to identify the genetic causes or predisposition to canine and human homologous genetic conditions. More recently, the idea emerged that dogs can be of help for therapeutic trials, to screen and validate new drugs in homologous human cancer types.


To this aim, we created the Cani-DNA biobank in 2003 to collect blood and tissue samples from dogs affected with genetic diseases and healthy dogs. Cani-DNA contains the native samples and extracted nucleic acids, as well as clinical and genealogical data, and distributes samples with quality-controlled procedures. This resource is implemented by a French veterinarian network based on vet practices, specialized vet centres and histopathology laboratories. In 2012, a contract signed between Cani-DNA and the 4 French vet schools and the Antagene company allowed a national organization and international visibility. Cani-DNA joined the French consortium of domesticated animals, CRB-Anim (funded by French government 2012-2020), aiming to combine genetic and reproductive resources.
To date, Cani-DNA, contains almost 21 000 DNA extracted from blood and 3000 nucleic acids (DNA, RNA) extracted from tissue samples (tumoral and controls), representing 300 breeds and over 100 genetic diseases (including several cancers like melanomas, lymphomas, gliomas and some rares human disorders like epilepsy, neuropathies, ocular diseases…. ).

 

Samples can be sent to implement Cani-DNA and can be distributed for research purposes, upon e-mail ordering (cani-dna@univ-rennes1.fr) or through: http://dog-genetics.genouest.org/. 

Contact us: 02 23 23 45 09 or by email cani-dna@univ-rennes1.fr

Subscribe to our newsletter