Staff scientist

Catherine ANDRÉ Group

+33 (0)2 23 23 67 60

Villejean campus / Building 4 / Room 219/1

In a few words

During my PhD in the "Dog Genetics" team at the IGDR, I worked on the definition of the rat and dog olfactory receptor gene repertoires and I studied the expression of this large family of genes in the rat olfactory epithelium.
In 2010, I joined Dr Elaine Ostrander's laboratory at the National Human Genome Research Institute in the USA; in her lab, I developed a project aiming at identifying genes involved in the differences in dog body size by using genotyping data from SNP chips and from canine whole-genome data.

Since April 2016, I'm working in the "Dog Genetics" team on a project aiming to identify the genes involved in canine hip dysplasia. I’m also working on a study on a renal disease affecting Dogues de Bordeaux (glomerulonephropathy).

Major publications

  • - Decker B*, Davis BW*, Rimbault M, Long AH, Karlins E, Jagannathan V, Reiman R, Parker HG, Drogemuller C, Corneveaux JJ, Chapman ES, Trent JM, Leeb T, Huentelman MJ, Wayne RK, Karyadi DM, Ostrander EA. Comparison against 186 canid whole genome sequences reveals survival strategies of an ancient clonally transmissible canine tumor. Genome Res. 2015 Nov;25(11):1646-55.

    - Rimbault M*, Beale HC*, Schoenebeck JJ, Hoopes BC, Allen JJ, Kilroy-Glynn P, Wayne RK, Sutter NB, Ostrander EA. Derived variants at six genes explain nearly half of size reduction in dog breeds. Genome Res. 2013 Dec;23(12):1985-95.

    - Hoopes BC, Rimbault M, Liebers D, Ostrander EA, Sutter NB. The insulin-like growth factor 1 receptor (IGF1R) contributes to reduced size in dogs. Mamm Genome. 2012 Dec;23(11-12):780-90.

    - Rimbault M, Ostrander EA. So many doggone traits: mapping genetics of multiple phenotypes in the domestic dog. Hum Mol Genet. 2012 Oct 15;21(R1):R52-7.

    - Rimbault M, Robin S, Vaysse A, Galibert F. RNA profiles of rat olfactory epithelia: individual and age related variations. BMC Genomics. 2009 Dec 2;10:572.

    - Quignon P, Giraud M, Rimbault M, Lavigne P, Tacher S, Morin E, Retout E, Valin AS, Lindblad-Toh K, Nicolas J, Galibert F. The dog and rat olfactory receptor repertoires. Genome Biol. 2005;6(10):R83.


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