• Lab manager


Shared responsibilities

  • Member of the Laboratory Council

In a few words

Claire Heichette obtained her diploma of Technician in Biochemistry in 1997 (Lycée Talensac, Nantes). In 1999, she joined the UMR 6026 "Cell and Molecular Interactions" of Rennes, in the teams "Structure and Dynamics of the Cytoskeleton" (Denis Chrétien), and "Channels and Membrane Receptors" (Daniel Thomas). She then belonged to the teams "Structure and Dynamics of Macromolecules" (2004-2007) and "Tubulin and Interacting Proteins" (since 2007) leaded by Denis Chrétien. In 2007, she obtained the grade of Technician in Biology, speciality Electron Microscopy, and in 2010 the grade of Technician in Biology, Class Exceptional. Claire shares today her activities between the functioning of the laboratory (lab manager) and that of the IGDR (prevention agent). She also teaches in the cryo-electron tomography workshops organized every year by the team.

Major publications

  • Trehalose prevents aggregation of exosomes and cryodamage
    Bosch S., de Beaurepaire L., Allard M., Mosser M., Heichette C., Chrétien D., Jegou D., and J.-M. Bach
    Scientific Reports, 2016 Nov.

    EB1 interacts with outwardly curved and straight regions of the microtubule lattice
    Guesdon A*, Bazile F*, Buey RM, Mohan R, Monier S, Rodríguez García R, Angevin M, Heichette C, Wieneke R, Tampé R, Duchesne L, Akhmanova A, Steinmetz MO, Chrétien D
    Nat Cell Biol, 2016 Sep.
    *Co-first authors

    Cryo-electron tomography of microtubules assembled in vitro from purified components
    Coquelle F., Blestel S., Heichette C., Arnal I., Kervrann C., Chrétien D
    Methods Mol Biol, 2011 Jun.

    The 90-kDa heat shock protein HSP90 protects tubulin against thermal denaturation
    Weis, F., Moullintraffort, L., Heichette, C., Chrétien, D., Garnier, C
    J Biol Chem, 2010, Mar.

    Second harmonic microscopy of axonemes
    Odin, C., Heichette, C., Chrétien,D., and Y. Le Grand
    Opt Express, 2009 May.

    EB1 regulates microtubule dynamics and tubulin sheet closure in vitro
    Vitre B, Coquelle FM, Heichette C, Garnier C, Chrétien D, Arnal I
    Nat Cell Biol, 2008 Apr.

    CLIP-170/tubulin-curved oligomers coassemble at microtubule ends and promote rescues
    Arnal I, Heichette C, Diamantopoulos GS, Chrétien D
    Curr Biol, 2004 Dec.

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