Gwenaël RABUT Group

Protein Ubiquitylation

Gwenaël RABUT

Group leader

> Email:

> Phone: +33 2 23 23 55 29


Our group is investigating ubiquitylation, a post-translational modification that regulates the activity of thousands of proteins in our cells and that is linked to a broad range of diseases, from cancers to neurodegenerative disorders.

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Major publications

Selected Publications

  • Protein quality control at the inner nuclear membrane.
    Khmelinskii A#, Blaszczak E#, Pantazopoulou M, Fischer B, Omnus DJ, Le Dez G, Brossard A, Gunnarsson A, Barry JD, Meurer M, Kirrmaier D, Boone C, Huber W, Rabut G*, Ljungdahl PO*, Knop M*. - * Corresponding authors - # Equal contribution
    Nature. 2014 Dec.

    CSN- and CAND1-dependent remodelling of the budding yeast SCF complex.
    Zemla A, Thomas Y, Kedziora S, Knebel A, Wood NT, Rabut G, Kurz T.
    Nat Commun. 2013 Mar.

    The TFIIH subunit Tfb3 regulates cullin neddylation.
    Rabut G*, Le Dez G, Verma R, Makhnevych T, Knebel A, Kurz T, Boone C, Deshaies RJ, Peter M*. - * Corresponding authors
    Mol Cell. 2011 Aug.

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