Thesis Prize 2019 of the Rennes 1 Foundation

Life Sciences (SDV)

1st Prize // Rafael Gomes Von Borowski Thesis supervisors: Reynald Gillet and Simone CB Gnioatto / Research unit: Institut de Génétique et Développement de Rennes (IGDR) Thesis topic: Bacteria produce an "adhesive film" called biofilm. It allows them to attach themselves in the human body and protect themselves against antibiotics and the immune system, triggering serious infections. We discovered a molecule (capsicumicin) from the C. baccatum pepper that destabilizes the biofilm, which then loses its protective properties. Bacteria can therefore be eliminated more easily.

2nd Prize // Nina Tardif Thesis supervisors: Marie Dominique Galibert and Sébastien Corre / Research unit: Institut de Génétique et Développement de Rennes (IGDR) Thesis topic: Discovery of the involvement of the AhR factor, hitherto known mainly for its protective role against environmental pollutants, in the development of resistance to certain melanoma treatments. This work thus opens up new therapeutic perspectives.