TIPs team publications

2010-2020

Structural model for differential cap maturation at growing microtubule ends 
Estévez-Gallego J*, Josa-Prado F*, Ku S*, Buey RM, Balaguer FA, Prota AE, Lucena-Agell D, Kamma-Lorger C, Yagi T, Iwamoto H, Duchesne L, Barasoain I, Steinmetz MO, Chrétien D, Kamimura S, Díaz JF, Oliva MA
Elife 2020 Mar.
*Co-first authors

A novel benzodiazepine derivative that suppresses microtubules dynamics and impairs mitotic progression
Pirani V, Metivier M, Gallaud E, Thomas A, Ku S, Chrétien D, Ettari R, Giet R, Corsi L, Benaud C
J. Cell. Sci., 2020 Feb.

Enhanced cell-cell contact stability and decreased N-cadherin-mediated migration upon fibroblast growth factor receptor-N-cadherin cross talk
Nguyen T, Duchesne L, Sankara Narayana GHN, Boggetto N, Fernig DD, Uttamrao Murade C, Ladoux B, Mège RM
Oncogene, 2019 Aug.

The Use of Cell-Free Xenopus Extracts to Investigate Cytoplasmic Events
Gibeaux R
, Heald R
Cold Spring Harb Protoc, 2019 Jun.

Lattice defects induce microtubule self-renewal
Schaedel L, Triclin S, Chrétien D, Abrieu A, Aumeier C, Gaillard J, Blanchoin L, Théry M, John K
Nature Physics, 2019, Jan.

Staphylococcus aureus Extracellular Vesicles Elicit an Immunostimulatory Response in vivo on the Murine Mammary Gland
Tartaglia NR, Breyne K, Meyer E, Cauty C, Jardin J, Chrétien D, Dupont A, Demeyere K, Berkova N, Azevedo V, Guédon E, Le Loir Y
Front. Cell. Infect. Microbiol., 2018 Aug.

Spindle assembly in egg extracts of the Marsabit clawed frog, Xenopus borealis.
Kitaoka M, Heald R, Gibeaux R
Cytoskeleton, 2018, Jun.

Subcellular scaling: Does size matter for cell division?
Heald R, Gibeaux R
Curr Opin Cell Biol, 2018, Jun.

Trehalose prevents aggregation of exosomes and cryodamage
Bosch S, de Beaurepaire L, Allard M, Mosser M, Heichette C, Chrétien D, Jegou D, and J.-M. Bach
Scientific Reports, 2016 Nov.

EB1 interacts with outwardly curved and straight regions of the microtubule lattice
Guesdon A*, Bazile F*, Buey RM, Mohan R, Monier S, Rodríguez García R, Angevin M, Heichette C, Wieneke R, Tampé R, Duchesne L, Akhmanova A, Steinmetz MO, Chrétien D
Nat Cell Biol. 2016 Sep.
*Co-first authors

Hsp90 directly interacts, in vitro, with amyloid structures and modulates their assembly and disassembly.
Schirmer C, Lepvrier E, Duchesne L, Decaux O, Thomas D, Delamarche C, Garnier C
Biochim Biophys Acta, 2016 Nov.

The formation of ordered nanoclusters controls cadherin anchoring to actin and cell–cell contact fluidity. 
Strale PO, Duchesne L, Peyret G, Montel L, Nguyen T, Png E, Tampé R, Troyanovsky S, Hénon S, Ladoux B, Mège RM
J Cell Biol. 2015 Jul.

Conditional Random Fields for tubulin-microtubule segmentation in cryo-electron tomography.
Kervrann C, Blestel S, Chrétien D
Proceedings of the IEEE International Conference on Image Processing (ICIP 2014), Paris. 2014 Oct. > pp 1-4 2014

Ensconsin/Map7 promotes microtubule growth and centrosome separation in Drosophila neural stem cells. 
Gallaud E, Caous R, Pascal A, Bazile F, Gagné JP, Huet S, Poirier GG, Chrétien D, Richard-Parpaillon L, Giet R
J Cell Biol. 2014 Mar.

Single versus dual-axis cryo-electron tomography of microtubules assembled in vitro: Limits and perspectives.
Guesdon A, Blestel S, Kervrann C, Chrétien D
J Struct Biol. 2013 Feb.

Transport of Fibroblast Growth Factor 2 in the Pericellular Matrix Is Controlled by the Spatial Distribution of Its Binding Sites in Heparan Sulfate. 
Duchesne L, Octeau V, Bearon RN, Beckett A, Prior I, Lounis B, Fernig DG
PLoS Biol. 2012 Jul.

Cryo-electron tomography of microtubules assembled in vitro from purified components.
Coquelle FM, Blestel S, Heichette C, Arnal I, Kervrann C, Chrétien D
Methods Mol Biol. 2011.

GDP-tubulin incorporation into growing microtubules modulates polymer stability.
Valiron O, Arnal I, Caudron N, Job D
J Biol Chem. 2010 Jun.

Procentriole assembly revealed by cryo-electron tomography.
Guichard P, Chrétien D, Marco S, Tassin AM
Embo J. 2010 May.

The 90-kDa heat shock protein HSP90 protects tubulin against thermal denaturation.
Weis F, Moullintraffort L, Heichette C, Chrétien D, Garnier C
J Biol Chem. 2010 Mar.

Before 2010

Small and stable peptidic PEGylated quantum dots to target polyhistidine-tagged proteins with controlled stoichiometry.
Dif A, Boulmedais F, Pinot M, Roullier V, Baudy-Floc'h M, Coquelle FM, Clarke S, Neveu P, Vignaux F, Le Borgne R, Dahan M, Gueroui Z, Marchi-Artzner V
J Am Chem Soc. 2009 Oct.

Structural basis of EB1 effects on microtubule dynamics.
Coquelle FM, Vitre B, Arnal I
Biochem Soc Trans. 2009 Oct.

Mercury (Drosophila Tubulin Binding Cofactor B) controls cell polarity through the stabilisation of the microtubule network.
Baffet A, Benoit B, Gourhand V, Heichette C, Chrétien D, Guichet A
Mech Dev. 2009 Aug.

A Fourier-based method for detecting curved microtubule centers: Application to straightening of cryo-electron microscope images.
Blestel S, Kervrann C, Chrétien D
Proceedings of the IEEE International Symposium on Biomedical Imaging: From Nano to Macro., Boston. 2009, June 28-July 1. > pp. 298-301.

Effects of confinement on the self-organization of microtubules and motors.
Pinot M, Chesnel F, Kubiak JZ, Arnal I, Nedelec FJ, Gueroui Z
Curr Biol. 2009 Jun.

Second harmonic microscopy of axonemes.
Odin C, Heichette C, Chrétien D, Le Grand Y
Opt Express. 2009 May.

Complex relationship between TCTP, microtubules and actin microfilaments regulates cell shape in normal and cancer cells.
Bazile F, Pascal A, Arnal I, Le Clainche C, Chesnel F, Kubiak JZ
Carcinogenesis. 2009 Apr.

EB1 regulates microtubule dynamics and tubulin sheet closure in vitro.
Vitre B, Coquelle FM, Heichette C, Garnier C, Chrétien D, Arnal I 
Nat Cell Biol. 2008 Apr.

Vitrification of dynamic microtubules.
Arnal I, Malleter M, Chrétien D
In: "Handbook of Cryopreparation Methods for Electron Microscopy", (eds: A. Cavalier, D. Spehner & B.M. Hembel). CRC Press, 2008.

Why is the microtubule lattice helical?
Hunyadi V, Chrétien D, Flyvbjerg H, Jánosi IM
Biol Cell. 2007 Feb.

Visualization of cell microtubules in their native state.
Bouchet-Marquis C, Zuber B, Glynn AM, Eltsov M, Grabenbauer M, Goldie KN, Thomas D, Frangakis AS, Dubochet J, Chrétien D
Biol Cell. 2007 Jan.

Water-soluble pegylated quantum dots: from a composite hexagonal phase to isolated micelles.
Boulmedais F, Bauchat P, Brienne MJ, Arnal I, Artzner F, Gacoin T, Dahan M, Marchi-Artzner V
Langmuir. 2006 Nov.

The evolving doublecortin (DCX) superfamily.
Reiner O, Coquelle FM, Peter B, Levy T, Kaplan A, Sapir T, Orr I, Barkai N, Eichele G, Bergmann S
BMC Genomics. 2006 Jul.

Global and local control of microtubule destabilization promoted by a catastrophe kinesin MCAK/XKCM1.
Kinoshita K, Noetzel TL, Arnal I, Drechsel DN, Hyman AA
J Muscle Res Cell Motil. 2006

Mechanical stress induced mechanism of microtubule catastrophes.
Hunyadi V, Chrétien D, Jánosi IM
J Mol Biol. 2005 May.

CLIP-170/tubulin-curved oligomers coassemble at microtubule ends and promote rescues. 
Arnal I, Heichette C, Diamantopoulos GS, Chrétien
Curr Biology. 2004 Dec.

Microtubule nucleation from stable tubulin oligomers.
Caudron, N., Arnal, I., Buhler, E., Job, D. and O. Valiron
J Biol Chem. 2002 Dec.

Structural microtubule cap: stability, catastrophe, rescue, and third state.
Jánosi IM, Chrétien D, Flyvbjerg H
Biophys J. 2002 Sep.

Dynamique du fuseau : vers une cible anti-cancéreuse.
Arnal I, Sassoon I, Tournebize R
Médecine et Science. 2002.

Microtubules switch occasionally into unfavorable configurations during elongation.
Chrétien D, Fuller SD
J Mol Biol. 2000 May.