Publications de l'équipe Mécanismes Moléculaires du Maintien de la polarité épithéliale


NB: les articles de l'équipe sont soumis à BioRxiv depuis 2017


Simultaneous regulation of cytokinetic furrow and nucleus positions by cortical tension contributes to proper DNA segregation during late mitosis
Pacquelet A, Jousseaume M, Etienne J, Michaux G.
2019, in press at Current Biology; 2019, BioRxiv

Force Transmission between Three Tissues Controls Bipolar Planar Polarity Establishment and Morphogenesis
Gillard G, Nicolle O, Brugière T, Prigent S, Pinot M, Michaux G.
2019, Current Biology; 2017, BioRXiv
Voir les actualités du CNRS et de l'Université de Rennes 1

V0-ATPase-dependent apical trafficking maintains the polarity of the intestinal absorptive membrane
Bidaud-Meynard A, Nicolle O, Heck M, Le Cunff Y, Michaux G.
2019, Development; 2018, BioRxiv


Dynamic formation of microvillus inclusions during enterocyte differentiation in Munc18-2 deficient intestinal organoids
Mosa MH, Nicolle O, Maschaldi S, Sepulveda FE, Bidaud-Meynard A, Menche C, Michels B, Michaux G*, de Saint Basile G*, Farin HF*. *Corresponding authors
2018, Cellular and Molecular Gastroenterology and Hepatology


Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity.
Salomon J, Gaston C, Magescas J, Duvauchelle B, Canioni D, Sengmanivong L, Mayeux A, Michaux G, Campeotto F, Lemale J, Viala J, Poirier F, Minc N, Schmitz J, Brousse N, Ladoux B, Goulet O, Delacour D.
2017, Nature Communications


The localisation of the apical Par/Cdc42 polarity module is specifically affected in microvillus inclusion disease.
Michaux G, Massey-Harroche D, Nicolle O, Rabant M, Brousse N, Goulet O, Le Bivic A, Ruemmele FM.
2016, Biology of the Cell


PAR-4 and anillin regulate myosin to coordinate spindle and furrow position during asymmetric division.
Pacquelet A, Uhart P, Tassan JP, Michaux G.
2015, Journal of Cell Biology
>> Journal of Cell Biology "biosight" video
>> CNRS highlight (in french)

Control of E-cadherin apical localisation and morphogenesis by a SOAP-1/AP-1/clathrin pathway in C. elegans epidermal cells.
Gillard G, Shafaq-Zadah M, Nicolle O, Damaj, R, Pécréaux J, Michaux G.
2015, Development
>> Journal cover

Adaptation of cryo-sectioning for immuno-EM-labeling of asymmetric samples: C. elegans case study.
Nicolle O, Burel A, Griffiths G, Michaux G, Kolotuev I.
2015, Traffic


GPSy: a cross-species gene prioritization system for conserved biological processes-application in male gamete development
Britto R, Sallou O, Collin O, Michaux G, Primig M, Chalmel F.
2012, Nucleic Acids Res.

AP-1 is required for the maintenance of apico-basal polarity in the C. elegans intestine. 
Shafaq-Zadah M, Brocard L, Solari F, Michaux G.
2012, Development
>> Highlighted in "In this issue" section


A role for Rab10 in Von Willebrand Factor release discovered by an AP-1 interactor screen in C. elegans. 
Michaux G*, Dyer CEF, Nightingale TD, Gallaud E, Nurrish S, Cutler DF*.
2011, J Thromb Haemost.

Anticancer drug 5-fluorouracil induces reproductive and developmental defects in Caenorhabditis elegans. 
Kumar S, Aninat C, Michaux G, Morel F.
2010, Reprod Toxicol.


[Sorting, recycling and WNT signaling: Wntless and retromer functions].
Michaux G, Le Borgne R.
Med Sci. 2009.
>> Review


High-pressure freezing provides insights into Weibel-Palade body biogenesis.
Zenner HL, Collinson LM, Michaux G, Cutler DF.
J Cell Sci. 2007

Genes required for osmoregulation and apical secretion in Caenorhabditis elegans.
Liégeois S, Benedetto A, Michaux G, Belliard G, Labouesse M.
Genetics. 2007


P-selectin and CD63 use different mechanisms for delivery to Weibel-Palade bodies.
Harrison-Lavoie KJ, Michaux G, Hewlett L, Kaur J, Hannah MJ, Lui-Roberts WW, Norman KE, Cutler DF.
Traffic. 2006

The physiological function of von Willebrand's factor depends on its tubular storage in endothelial Weibel-Palade bodies.
Michaux G, Abbitt KB, Collinson LM, Haberichter SL, Norman KE, Cutler DF.
Dev Cell. 2006 Feb.

P-selectin binds to the D'-D3 domains of von Willebrand factor in Weibel-Palade bodies.
Michaux G, Pullen TJ, Haberichter SL, Cutler DF.
Blood. 2006 May.


An AP-1/clathrin coat plays a novel and essential role in forming the Weibel-Palade bodies of endothelial cells.
Lui-Roberts WW, Collinson LM, Hewlett LJ, Michaux G, Cutler DF.
J Cell Biol. 2005


CLN6, which is associated with a lysosomal storage disease, is an endoplasmic reticulum protein.
Mole SE, Michaux G, Codlin S, Wheeler RB, Sharp JD, Cutler DF.
Exp Cell Res. 2004

How to roll an endothelial cigar: the biogenesis of Weibel-Palade bodies.
Michaux G, Cutler DF.
Traffic. 2004
>> Review.


Analysis of intracellular storage and regulated secretion of 3 von Willebrand disease-causing variants of von Willebrand factor.
Michaux G, Hewlett LJ, Messenger SL, Goodeve AC, Peake IR, Daly ME, Cutler DF.
Blood. 2003


Epithelial biology: lessons from Caenorhabditis elegans.
Michaux G, Legouis R, Labouesse M.
Gene. 2001
>> Review.

The Caenorhabditis elegans gene lin-26 can trigger epithelial differentiation without conferring tissue specificity.
Quintin S, Michaux G, McMahon L, Gansmuller A, Labouesse M.
Dev Biol. 2001


CHE-14, a protein with a sterol-sensing domain, is required for apical sorting in C. elegans ectodermal epithelial cells.
Michaux G, Gansmuller A, Hindelang C, Labouesse M.
Curr Biol. 2000


Sequence and analysis of a 26.9 kb fragment from chromosome XV of the yeast Saccharomyces cerevisiae.
Boyer J, Michaux G, Fairhead C, Gaillon L, Dujon B.
Yeast. 1996


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