Publications de l'équipe ODIM

Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Cav1.2 channels.
Rougier JS, Albesa M, Syam N, Halet G, Abriel H, Viard P.
Pflugers Arch. 2015 Sep.

Novel role for p110β PI 3-kinase in male fertility through regulation of androgen receptor activity in Sertoli cells. 
Guillermet-Guibert J, Smith LB, Halet G, Whitehead MA, Pearce W, Rebourcet D, Leon K, Crépieux P, Nock G, Stromstedt M, Enerback M, Chelala C, Graupera M, Carroll J, Cosulich S, Saunders PT, Huhtaniemi I, Vanhaesebroeck B.
PLoS Genetics. 2015 Jul.

Ran promotes oocyte polarization by regulating ERM (Ezrin/Radixin/Moesin) inactivation. 
Dehapiot B, Halet G.
Cell Cycle. 2013 Jun.

Polarized Cdc42 activation promotes polar body protrusion and asymmetric division in mouse oocytes. 
Dehapiot B, Carrière V, Carroll J, Halet G.
Dev Biol. 2013 May.

Cdk1, but not Cdk2, is the sole Cdk that is essential and sufficient to drive resumption of meiosis in mouse oocytes. 
Adhikari D, Zheng W, Shen Y, Gorre N, Ning Y, Halet G, Kaldis P and Liu K. 
Hum Mol Genet. 2012 Jun.

Involvement of ITIH5, a Candidate Gene for Congenital Uterovaginal Aplasia (Mayer-Rokitansky-Küster-Hauser Syndrome), in Female Genital Tract Development. 
Morcel, K, Watrin T, Jaffre F, Deschamps S, Omilli F, Pellerin I, Levêque J, Guerrier D.
Gene Expr. 2012.

Regulation of diacylglycerol production and protein kinase C stimulation during sperm and PLCzeta-mediated mouse egg activation. 
Yu Y, Halet G, Lai A, Swann K.
Biol Cell. 2008 Nov.

Regulation of cytosolic and mitochondrial ATP levels in mouse eggs and zygotes. 
Dumollard R, Campbell K, Halet G, Carroll J, Swann K.
Dev. Biol. 2008 Apr.

Constitutive PtdIns(3,4,5)P3 synthesis promotes the development and survival of early mammalian embryos.
Halet G, Viard P, Carroll J.
Development. 2008 Feb.

Lipid binding proteins to study localization of phosphoinositides.
Halet G and Viard P.
In: "Probes and Tags to Study Biomolecular Function: for Proteins, RNA, and Membranes" (ed L. W. Miller), Wiley-VCH Verlag GmbH & Co, KGaA, Weinheim, Germany, 2008.

Rac activity is polarized and regulates meiotic spindle stability and anchoring in mammalian oocytes. 
Halet G, Carroll J.
Dev Cell. 2007 Feb.

The absence of a Ca2+ signal during mouse egg activation can affect parthenogenetic preimplantation development, gene expression patterns, and blastocyst quality. 
Rogers NT, Halet G, Piao Y, Carroll J, Ko MS, Swann K.
Reproduction. 2006 Jul.

Imaging phosphoinositide dynamics using GFP-tagged protein domains. 
Halet G.
Biol Cell. 2005 Jul.

PKC signaling at fertilization in mammalian eggs. 
Halet G.
Biochim Biophys Acta. 2004 Dec.

PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane. 
Viard P, Butcher AJ, Halet G, Davies A, Nurnberg B, Heblich F, Dolphin AC.
Nat Neurosci. 2004 Sep.

Ca2+ signalling and cortical re-organisation during the transition from meiosis to mitosis in mammalian oocytes. 
Carroll J, FitzHarris G, Marangos P, Halet G.
Eur J Obstet Gynecol Reprod Biol. 2004 Jul.

Conventional PKCs regulate the temporal pattern of Ca2+ oscillations at fertilization in mouse eggs.
Halet G, Tunwell R, Parkinson SJ, Carroll J.
J Cell Biol. 2004 Mar

Ca2+ oscillations at fertilization in mammals.
Halet G, Marangos, FitzHarris G, Carroll J.
Biochem Soc Trans. 2003 Oct.

The dynamics of plasma membrane PtdIns(4,5)P2 at fertilization of mouse eggs. 
Halet G, Tunwell R, Balla T, Swann K, Carroll J.
J Cell Sci. 2002.